FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

SUMO activating enzyme activity

ID (Ontology)

GO:0019948 (Gene Ontology)

Definition

Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.[ PubMed:10187858 PubMed:11265250 ]

Also Known As

"SMT3 activating enzyme" ; "SUMO E1 activator enzyme"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
SUMO activating enzyme activity (all annotations which use CV term, excluding "NOT" statements)
contributes_to \| SUMO activating enzyme activity	--
enables \| SUMO activating enzyme activity	--

Spanning Tree (Parents/Children)

ligase activity, forming carbon-sulfur bonds__
catalytic activity, acting on a protein_______|
ATP-dependent activity________________________|
                                              ubiquitin-like modifier activating enzyme activity
                                               |__SUMO activating enzyme activity  3 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	ubiquitin-like modifier activating enzyme activity
Part of
Synonyms & Secondary IDs
Synonyms
	"SMT3 activating enzyme" EXACT "SUMO E1 activator enzyme" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-2990833 "Conjugation of SUMO1 to UBA2:SAE1" Reactome:R-HSA-2993781 "Conjugation of SUMO3 to UBA2:SAE1" Reactome:R-HSA-2993784 "Conjugation of SUMO2 to UBA2:SAE1"