FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term SUMO activating enzyme activity ID (Ontology) GO:0019948 (Gene Ontology)
Definition Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.[ PubMed:10187858 PubMed:11265250 ]
Also Known As "SMT3 activating enzyme" ; "SUMO E1 activator enzyme"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 SUMO activating enzyme activity (all annotations which use CV term, excluding "NOT" statements)       1      2
     contributes_to | SUMO activating enzyme activity       --       2
     enables | SUMO activating enzyme activity       --       1
Spanning Tree (Parents/Children)
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ligase activity, forming carbon-sulfur bonds__
catalytic activity, acting on a protein_______|
ATP-dependent activity________________________|
                                              ubiquitin-like modifier activating enzyme activity
                                               |__SUMO activating enzyme activity  3 rec.
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Is a ubiquitin-like modifier activating enzyme activity
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Synonyms
  • "SMT3 activating enzyme" EXACT
    "SUMO E1 activator enzyme" EXACT
Secondary IDs
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Reactome:R-HSA-2990833 "Conjugation of SUMO1 to UBA2:SAE1"
Reactome:R-HSA-2993781 "Conjugation of SUMO3 to UBA2:SAE1"
Reactome:R-HSA-2993784 "Conjugation of SUMO2 to UBA2:SAE1"