FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term ligand-gated channel activity ID (Ontology) GO:0022834 (Gene Ontology)
Definition Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.[ ISBN:0815340729 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 ligand-gated channel activity (all annotations which use CV term, excluding "NOT" statements)
     enables | ligand-gated channel activity       --
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  channel activity
   |__gated channel activity
       |__ligand-gated channel activity  312 rec.
           |__ATP-gated ion channel activity
           |   |__extracellularly ATP-gated monoatomic cation channel activity
           |   |__intracellularly ATP-gated ion channel activity(+)
           |   |__mitochondrial ATP-gated potassium channel activity
           |__intracellularly calcium-gated channel activity 8 rec.
           |   |__intracellularly calcium-gated chloride channel activity 8 rec.
           |__ligand-gated monoatomic ion channel activity 297 rec.
           |   |__cyclic nucleotide-activated monoatomic ion channel activity(+) 7 rec.
           |   |__extracellular ligand-gated monoatomic ion channel activity(+) 53 rec.
           |   |__intracellularly ligand-gated monoatomic ion channel activity(+) 15 rec.
           |   |__ionotropic olfactory receptor activity 60 rec.
           |   |__ionotropic taste receptor activity(+) 16 rec.
           |   |__ligand-gated monoatomic anion channel activity(+) 20 rec.
           |   |__ligand-gated monoatomic cation channel activity(+) 94 rec.
           |   |__ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
           |   |__pH-gated monoatomic ion channel activity(+) 10 rec.
           |__monoatomic ion-gated channel activity 14 rec.
           |   |__calcium-activated cation channel activity(+) 10 rec.
           |   |__chloride-activated potassium channel activity
           |   |__intracellular sodium-activated potassium channel activity 2 rec.
           |__transmitter-gated channel activity 43 rec.
               |__transmitter-gated monoatomic ion channel activity(+) 43 rec.
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