FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term L-malate dehydrogenase (NAD+) activity ID (Ontology) GO:0030060 (Gene Ontology)
Definition Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.
Also Known As "NAD-L-malate dehydrogenase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       4
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 L-malate dehydrogenase (NAD+) activity (all annotations which use CV term, excluding "NOT" statements)       1      4
     enables | L-malate dehydrogenase (NAD+) activity       --       4
Spanning Tree (Parents/Children)
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oxidoreductase activity, acting on CH-OH group of donors
 |__malate dehydrogenase activity__________________________________________________________
 |__oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor__|
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Is a malate dehydrogenase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Part of
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Synonyms
  • "(S)-malate:NAD+ oxidoreductase activity" RELATED[ EC:1 ]
    "L-malate-NAD+ oxidoreductase activity" RELATED[ EC:1 ]
    "malate (NAD) dehydrogenase activity" RELATED[ EC:1 ]
    "malic acid dehydrogenase activity" RELATED[ EC:1 ]
    "malic dehydrogenase activity" RELATED[ EC:1 ]
    "MDH" RELATED[ EC:1 ]
    "NAD-dependent malate dehydrogenase activity" RELATED[ EC:1 ]
    "NAD-dependent malic dehydrogenase activity" RELATED[ EC:1 ]
    "NAD-L-malate dehydrogenase activity" EXACT
    "NAD-linked malate dehydrogenase activity" RELATED[ EC:1 ]
    "NAD-malate dehydrogenase activity" RELATED[ EC:1 ]
    "NAD-malic dehydrogenase activity" RELATED[ EC:1 ]
    "NAD-specific malate dehydrogenase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.1.1.37
MetaCyc:MALATE-DEH-RXN
Reactome:R-HSA-70979 "MDH2 dimer dehydrogenates MAL"
Reactome:R-HSA-9856871 "MDH1 reduces OA"
RHEA:21432