FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

regulation of mitotic metaphase/anaphase transition

ID (Ontology)

GO:0030071 (Gene Ontology)

Definition

Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.

Comment

Links to External Ontologies

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Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
regulation of mitotic metaphase/anaphase transition (all annotations which use CV term, excluding "NOT" statements)
involved_in \| regulation of mitotic metaphase/anaphase transition

Spanning Tree (Parents/Children)

regulation of mitotic cell cycle
 |__regulation of mitotic cell cycle phase transition__________
regulation of sister chromatid segregation                     |
 |__regulation of metaphase/anaphase transition of cell cycle__|
mitotic cell cycle phase transition                            |
 |__metaphase/anaphase transition of mitotic cell cycle________|
 |__regulation of mitotic cell cycle phase transition__________|
metaphase/anaphase transition of cell cycle                    |
 |__metaphase/anaphase transition of mitotic cell cycle________|
 |__regulation of metaphase/anaphase transition of cell cycle__|
regulation of cell cycle phase transition                      |
 |__regulation of mitotic cell cycle phase transition__________|
 |__regulation of metaphase/anaphase transition of cell cycle__|
                                                               regulation of mitotic metaphase/anaphase transition  27 rec.
                                                                |__negative regulation of mitotic metaphase/anaphase transition 13 rec.
                                                                |   |__mitotic spindle assembly checkpoint signaling(+) 13 rec.
                                                                |__positive regulation of mitotic metaphase/anaphase transition 10 rec.
                                                                |   |__negative regulation of mitotic spindle assembly checkpoint signaling(+)
                                                                |__regulation of mitotic cell cycle spindle assembly checkpoint 4 rec.
                                                                    |__negative regulation of mitotic spindle assembly checkpoint signaling(+)
                                                                    |__positive regulation of mitotic cell cycle spindle assembly checkpoint(+) 1 rec.

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Relationships
Is a	regulation of mitotic cell cycle phase transition regulation of metaphase/anaphase transition of cell cycle
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Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts