FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term AP-1 adaptor complex ID (Ontology) GO:0030121 (Gene Ontology)
Definition A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).[ PubMed:10611976 PubMed:21097499 ]
Also Known As"HA1" ; "HA1 clathrin adaptor"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 AP-1 adaptor complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | AP-1 adaptor complex       --
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Golgi apparatus
 |__clathrin coat of trans-Golgi network vesicle__
trans-Golgi network transport vesicle membrane    |
 |__clathrin coat of trans-Golgi network vesicle__|
clathrin coat                                     |
 |__clathrin adaptor complex______________________|
AP-type membrane coat adaptor complex             |
 |__clathrin adaptor complex______________________|
clathrin vesicle coat                             |
 |__clathrin coat of trans-Golgi network vesicle__|
                                                  AP-1 adaptor complex  7 rec.
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Is a clathrin adaptor complex
Part of clathrin coat of trans-Golgi network vesicle
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Synonyms
  • "AP-1 related adapter complex" RELATED
    "HA1" EXACT
    "HA1 clathrin adaptor" EXACT
Secondary IDs
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