FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

AP-3 adaptor complex

ID (Ontology)

GO:0030123 (Gene Ontology)

Definition

A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).[ PubMed:10611976 PubMed:21097499 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
AP-3 adaptor complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| AP-3 adaptor complex	--

Spanning Tree (Parents/Children)

membrane coat_____________
membrane protein complex__|
                          AP-type membrane coat adaptor complex
                           |__AP-3 adaptor complex  5 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	AP-type membrane coat adaptor complex
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts