FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term heparan sulfate proteoglycan catabolic process ID (Ontology) GO:0030200 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of heparan sulfate proteoglycans, which consist of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids.[ PubMed:35536982 ]
Also Known As "heparan sulfate proteoglycan breakdown" ; "heparan sulfate proteoglycan catabolism" ; "heparan sulfate proteoglycan degradation" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       8
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 Gene Groups Genes
 heparan sulfate proteoglycan catabolic process (all annotations which use CV term, excluding "NOT" statements)       1      8
     involved_in | heparan sulfate proteoglycan catabolic process       --       8
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proteoglycan metabolic process
 |__proteoglycan catabolic process__________________
 |__heparan sulfate proteoglycan metabolic process__|
glycoprotein catabolic process                      |
 |__proteoglycan catabolic process__________________|
                                                    heparan sulfate proteoglycan catabolic process  9 rec.
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Is a proteoglycan catabolic process
heparan sulfate proteoglycan metabolic process
Part of
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Synonyms
  • "heparan sulfate proteoglycan breakdown" EXACT
    "heparan sulfate proteoglycan catabolism" EXACT
    "heparan sulfate proteoglycan degradation" EXACT
    "heparan sulphate proteoglycan catabolic process" EXACT
    "heparan sulphate proteoglycan catabolism" EXACT
    "heparin proteoglycan catabolic process" RELATED
Secondary IDs
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Reactome:R-HSA-2024096 "HS-GAG degradation"