FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

phospholipase C-activating opsin-mediated signaling pathway

ID (Ontology)

GO:0030265 (Gene Ontology)

Definition

A phospholipase C-activating receptor G protein-coupled receptor signaling pathway that starts with an opsin being activated by a photon, and transmitting the signal through the Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). The second messengers, including cGMP, activate channels that result in transmission of the light signal through the synapses. Typical examples are rhabdomeric photoreceptors in the eyes of protostomes.[ PubMed:19720651 PubMed:22498302 PubMed:8823931 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
phospholipase C-activating opsin-mediated signaling pathway (all annotations which use CV term, excluding "NOT" statements)
involved_in \| phospholipase C-activating opsin-mediated signaling pathway

Spanning Tree (Parents/Children)

G protein-coupled receptor signaling pathway
 |__phospholipase C-activating G protein-coupled receptor signaling pathway__
 |__G protein-coupled opsin signaling pathway________________________________|
phototransduction                                                            |
 |__G protein-coupled opsin signaling pathway________________________________|
phototransduction, visible light                                             |
 |__G protein-coupled opsin signaling pathway________________________________|
cellular response to light stimulus                                          |
 |__G protein-coupled opsin signaling pathway________________________________|
                                                                             phospholipase C-activating opsin-mediated signaling pathway  6 rec.

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Relationships
Is a	phospholipase C-activating G protein-coupled receptor signaling pathway G protein-coupled opsin signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"phospholipase C-activating rhodopsin mediated G-protein coupled receptor signaling pathway" NARROW "phospholipase C-activating rhodopsin mediated signaling pathway" NARROW "PLC-activating rhodopsin mediated signaling pathway" NARROW "rhodopsin mediated G protein signaling, coupled to IP3 second messenger" NARROW "rhodopsin mediated G protein signalling, coupled to IP3 second messenger" NARROW "rhodopsin mediated G-protein signaling, coupled to IP3 second messenger" NARROW "rhodopsin mediated G-protein signalling, coupled to IP3 second messenger" NARROW
Secondary IDs

External Crossreferences & Linkouts