FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity ID (Ontology) GO:0030342 (Gene Ontology)
Definition Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).[ PubMed:8506296 ]
Also Known As "1,25-(OH)2D3 24-hydroxylase activity" ; "calcitriol 24-hydroxylase activity"
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity       1
Spanning Tree (Parents/Children)
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  steroid hydroxylase activity
   |__vitamin D 24-hydroxylase activity
       |__1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity  1 rec.
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Is a vitamin D 24-hydroxylase activity
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Synonyms
  • "1,25-(OH)2D3 24-hydroxylase activity" EXACT[ PubMed:8506296 ]
    "calcitriol 24-hydroxylase activity" EXACT
Secondary IDs
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Reactome:R-HSA-209765 "CYP24A1 hydroxylates 1,25(OH)2D, inactivating it"
Reactome:R-HSA-211950 "CYP24A1 24-hydroxylates CTL"
Reactome:R-HSA-5602004 "Defective CYP24A1 does not 24-hydroxylate CALTOL"
RHEA:24964