FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent ID (Ontology) GO:0030697 (Gene Ontology)
Definition Catalysis of the reaction: S-adenosyl-L-methionine + uridine54 in tRNA = 5-methyluridine54 in tRNA + H+ + S-adenosyl-L-homocysteine.
Also Known As "S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity" ; "S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity" ; "tRNA (uracil(54)-C(5))-methyltransferase activity, S-adenosyl methionine-dependent"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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Relevant FlyBase reports
 Genes
 tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent (all annotations which use CV term, excluding "NOT" statements)
     enables | tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent
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methyltransferase activity
 |__S-adenosylmethionine-dependent methyltransferase activity__
tRNA methyltransferase activity                                |
 |__tRNA (uridine) methyltransferase activity__________________|
                                                               tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent  1 rec.
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Is a S-adenosylmethionine-dependent methyltransferase activity
tRNA (uridine) methyltransferase activity
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Synonyms
  • "M5U-methyltransferase activity" RELATED[ EC:2 ]
    "ribothymidyl synthase activity" BROAD[ EC:2 ]
    "RUMT" BROAD
    "RUMT activity" RELATED[ EC:2 ]
    "S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity" EXACT
    "S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity" RELATED[ EC:2 ]
    "S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity" EXACT
    "transfer RNA uracil 5-methyltransferase activity" RELATED[ EC:2 ]
    "transfer RNA uracil methylase activity" RELATED[ EC:2 ]
    "tRNA (uracil(54)-C(5))-methyltransferase activity, S-adenosyl methionine-dependent" EXACT
    "tRNA (uracil-5-)-methyltransferase activity" BROAD
    "tRNA uracil 5-methyltransferase activity" RELATED[ EC:2 ]
    "tRNA:m(5)U54-methyltransferase activity" RELATED[ EC:2 ]
    "tRNA:m5U54-methyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.1.1.35
MetaCyc:TRNA-URACIL-5--METHYLTRANSFERASE-RXN
RHEA:42712