FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

Mre11 complex

ID (Ontology)

GO:0030870 (Gene Ontology)

Definition

Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.[ PubMed:11988766 PubMed:17674145 ]

Also Known As

"MRN complex" ; "MRX complex" ; "Rad50 complex" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
Mre11 complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| Mre11 complex	--

Spanning Tree (Parents/Children)

nucleus_____________________
protein-containing complex__|
                            nuclear protein-containing complex
                             |__Mre11 complex  4 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	nuclear protein-containing complex
Part of
Synonyms & Secondary IDs
Synonyms
	"MRN complex" EXACT "MRX complex" EXACT "Rad50 complex" EXACT "RAD50-MRE11-NBN complex" EXACT "Rad50-Rad32-Nbs1 complex" EXACT "RMX complex" EXACT
Secondary IDs

External Crossreferences & Linkouts