FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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Term retromer complex ID (Ontology) GO:0030904 (Gene Ontology)
Definition A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.[ PubMed:26220253 PubMed:27385586 PubMed:9700157 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
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 retromer complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | retromer complex       --
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membrane
 |__membrane protein complex___
protein-containing complex     |
 |__membrane protein complex___|
cellular anatomical structure  |
 |__endomembrane system________|
                               retromer complex  8 rec.
                                |__retromer, cargo-selective complex 4 rec.
                                |__retromer, tubulation complex 2 rec.
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Is a membrane protein complex
Part of endomembrane system
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