FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term retromer, tubulation complex ID (Ontology) GO:0030905 (Gene Ontology)
Definition The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodeling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.[ PubMed:26220253 PubMed:9700157 ]
Also Known As"heterodimeric membrane-deforming retromer subcomplex" ; "retromer complex, outer shell" ; "SNX-BAR dimer"
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 retromer, tubulation complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | retromer, tubulation complex
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endomembrane system
 |__retromer complex__________
membrane                      |
 |__membrane protein complex__|
protein-containing complex    |
 |__membrane protein complex__|
membrane protein complex      |
 |__retromer complex__________|
                              retromer, tubulation complex  2 rec.
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Is a membrane protein complex
Part of retromer complex
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Synonyms
  • "heterodimeric membrane-deforming retromer subcomplex" EXACT[ PubMed:22193161 ]
    "retromer complex, outer shell" EXACT
    "SNX-BAR dimer" EXACT[ PubMed:26220253 ]
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