FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term retromer, cargo-selective complex ID (Ontology) GO:0030906 (Gene Ontology)
Definition The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.[ PubMed:11102511 PubMed:26220253 PubMed:9700157 ]
Also Known As "cargo-selective retromer subcomplex" ; "retromer complex, inner shell" ; "retromer CSC" (for all, see Synonyms field below)
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       4
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 Genes
 retromer, cargo-selective complex (all annotations which use CV term, excluding "NOT" statements)       4
     part_of | retromer, cargo-selective complex       4
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endomembrane system
 |__retromer complex__________
membrane                      |
 |__membrane protein complex__|
protein-containing complex    |
 |__membrane protein complex__|
membrane protein complex      |
 |__retromer complex__________|
                              retromer, cargo-selective complex  4 rec.
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Is a membrane protein complex
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