FB2026_03 , released September 17, 2026
CV Term Report
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Term Smc5-Smc6 complex ID (Ontology) GO:0030915 (Gene Ontology)
Definition A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.[ PubMed:14701739 PubMed:15738391 PubMed:27373152 ]
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 Smc5-Smc6 complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | Smc5-Smc6 complex       --
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chromosome
 |__condensed chromosome__
transferase complex       |
 |__SUMO ligase complex___|
                          Smc5-Smc6 complex  11 rec.
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Is a SUMO ligase complex
Part of condensed chromosome
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