FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term retrograde protein transport, ER to cytosol ID (Ontology) GO:0030970 (Gene Ontology)
Definition The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.[ PubMed:11994744 ]
Also Known As"protein dislocation from ER" ; "protein retrotranslocation, ER to cytosol" ; "retrograde protein transport, endoplasmic reticulum to cytosol"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 retrograde protein transport, ER to cytosol (all annotations which use CV term, excluding "NOT" statements)
     involved_in | retrograde protein transport, ER to cytosol
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transport
 |__protein transport_____________________
intracellular protein localization        |
 |__protein transport_____________________|
proteasomal protein catabolic process     |
 |__ERAD pathway__________________________|
response to endoplasmic reticulum stress  |
 |__ERAD pathway__________________________|
response to chemical                      |
 |__ERAD pathway__________________________|
establishment of protein localization     |
 |__protein transport_____________________|
                                          retrograde protein transport, ER to cytosol  4 rec.
                                           |__regulation of retrograde protein transport, ER to cytosol 1 rec.
                                               |__negative regulation of retrograde protein transport, ER to cytosol 1 rec.
                                               |__positive regulation of retrograde protein transport, ER to cytosol
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Is a protein transport
Part of ERAD pathway
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Synonyms
  • "protein dislocation from ER" EXACT
    "protein retrotranslocation, ER to cytosol" EXACT
    "retrograde protein transport, endoplasmic reticulum to cytosol" EXACT
Secondary IDs
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