FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

regulatory ncRNA-mediated heterochromatin formation

ID (Ontology)

GO:0031048 (Gene Ontology)

Definition

A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginning of trancription.[ PubMed:19239886 PubMed:21420348 ]

Also Known As

"ncRNA-mediated heterochromatin formation" ; "RNA interference-like chromatin silencing" ; "RNA-dependent heterochromatin formation" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
regulatory ncRNA-mediated heterochromatin formation (all annotations which use CV term, excluding "NOT" statements)
involved_in \| regulatory ncRNA-mediated heterochromatin formation

Spanning Tree (Parents/Children)

negative regulation of gene expression
 |__regulatory ncRNA-mediated gene silencing________
cellular component assembly                         |
 |__heterochromatin formation_______________________|
negative regulation of gene expression, epigenetic  |
 |__heterochromatin formation_______________________|
heterochromatin organization                        |
 |__heterochromatin formation_______________________|
                                                    regulatory ncRNA-mediated heterochromatin formation  35 rec.
                                                     |__piRNA-mediated heterochromatin formation 24 rec.
                                                     |   |__gene silencing by piRNA-directed DNA methylation(+)
                                                     |   |__transposable element silencing by piRNA-mediated heterochromatin formation 24 rec.
                                                     |__regulation of regulatory ncRNA-mediated heterochromatin formation 1 rec.
                                                     |   |__negative regulation of regulatory ncRNA-mediated heterochromatin formation 1 rec.
                                                     |   |__regulation of siRNA-mediated facultative heterochromatin formation
                                                     |__siRNA-mediated heterochromatin formation 6 rec.
                                                         |__gene silencing by siRNA-directed DNA methylation(+)
                                                         |__siRNA-mediated facultative heterochromatin formation(+)
                                                         |__siRNA-mediated pericentric heterochromatin formation 2 rec.
                                                         |__siRNA-mediated silent mating type cassette region heterochromatin formation
                                                         |__transposable element silencing by siRNA-mediated heterochromatin formation

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	regulatory ncRNA-mediated gene silencing heterochromatin formation
Part of
Synonyms & Secondary IDs
Synonyms
	"chromatin silencing by small RNA" RELATED "heterochromatin assembly by small RNA" NARROW "heterochromatin assembly involved in chromatin silencing by small RNA" RELATED "heterochromatin formation involved in chromatin silencing by small RNA" RELATED "ncRNA-mediated heterochromatin formation" EXACT "pre-transcriptional gene silencing by RNA" BROAD "pre-transcriptional gene silencing by small non-coding RNA" NARROW "RNA interference-like chromatin silencing" EXACT "RNA-dependent heterochromatin formation" EXACT "RNA-mediated chromatin silencing" EXACT "RNA-mediated heterochromatin formation" RELATED "RNA-mediated TGS" BROAD "RNA-mediated transcriptional silencing" EXACT "RNAi-directed chromatin silencing" EXACT "RNAi-like chromatin silencing" EXACT "small ncRNA-mediated heterochromatin formation" NARROW "small non-coding RNA-dependent heterochromatin formation" NARROW "small RNA-mediated heterochromatic silencing" NARROW "small RNA-mediated heterochromatin formation" NARROW
Secondary IDs

External Crossreferences & Linkouts