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| Term | nuclear pore outer ring | ID (Ontology) | GO:0031080 (Gene Ontology) |
| Definition | A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates).[ PubMed:18046406 PubMed:19524430 PubMed:20947011 PubMed:22419078 ] | ||
| Also Known As | "Nup107-120 complex" ; "Nup107-160 complex" ; "Nup84 complex" | ||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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nucleus |__nuclear protein-containing complex__ nuclear envelope | |__nuclear pore________________________| protein-containing complex | |__nuclear protein-containing complex__| nuclear protein-containing complex | |__nuclear pore________________________| nuclear pore outer ring 8 rec. |
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| Is a | nuclear protein-containing complex | ||
| Part of | nuclear pore | ||
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