FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ID (Ontology) GO:0031146 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.[ PubMed:15380083 ]
Also Known As"SCF-dependent proteasomal ubiquitin-dependent protein breakdown" ; "SCF-dependent proteasomal ubiquitin-dependent protein catabolism" ; "SCF-dependent proteasomal ubiquitin-dependent protein degradation"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process       --
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ubiquitin-dependent protein catabolic process__
proteasomal protein catabolic process__________|
                                               proteasome-mediated ubiquitin-dependent protein catabolic process
                                                |__SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  69 rec.
                                                    |__regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1 rec.
                                                        |__negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process 1 rec.
                                                        |__positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process
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Is a proteasome-mediated ubiquitin-dependent protein catabolic process
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Synonyms
  • "SCF-dependent proteasomal ubiquitin-dependent protein breakdown" EXACT
    "SCF-dependent proteasomal ubiquitin-dependent protein catabolism" EXACT
    "SCF-dependent proteasomal ubiquitin-dependent protein degradation" EXACT
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