FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term DNA replication preinitiation complex ID (Ontology) GO:0031261 (Gene Ontology)
Definition A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.[ PubMed:12694535 PubMed:15194812 PubMed:17230184 ]
Also Known As "pre-IC"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 DNA replication preinitiation complex (all annotations which use CV term, excluding "NOT" statements)       2
     part_of | DNA replication preinitiation complex       2
Spanning Tree (Parents/Children)
Only view relationship: 
nucleus
 |__nuclear protein-containing complex__
nuclear lumen                           |
 |__nucleoplasm_________________________|
protein-containing complex              |
 |__protein-DNA complex_________________|
 |__nuclear protein-containing complex__|
cellular anatomical structure           |
 |__nucleoplasm_________________________|
                                        DNA replication preinitiation complex  14 rec.
                                         |__CMG complex 12 rec.
                                         |__GINS complex 5 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a protein-DNA complex
nuclear protein-containing complex
Part of nucleoplasm
hide Synonyms & Secondary IDs
Synonyms
  • "pre-IC" EXACT
Secondary IDs
hide External Crossreferences & Linkouts