FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

CD95 death-inducing signaling complex

ID (Ontology)

GO:0031265 (Gene Ontology)

Definition

A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.[ PubMed:12628743 PubMed:12655293 ]

Also Known As

"CD95 death-inducing signalling complex" ; "CD95 DISC" ; "Fas death-inducing signaling complex"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
CD95 death-inducing signaling complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| CD95 death-inducing signaling complex

Spanning Tree (Parents/Children)

  plasma membrane protein complex
   |__death-inducing signaling complex
       |__CD95 death-inducing signaling complex  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	death-inducing signaling complex
Part of
Synonyms & Secondary IDs
Synonyms
	"CD95 death-inducing signalling complex" EXACT "CD95 DISC" EXACT "Fas death-inducing signaling complex" EXACT
Secondary IDs

External Crossreferences & Linkouts