FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term replication fork protection complex ID (Ontology) GO:0031298 (Gene Ontology)
Definition A heterotrimeric replication-pausing complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling. Required for maximal fork speed both in vivo and in vitro.[ PubMed:12944972 PubMed:15367656 PubMed:19819872 ]
Also Known As "fork pausing complex" ; "FPC"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_CELLULAR_COMPONENT
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 replication fork protection complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | replication fork protection complex
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nuclear chromosome
 |__nuclear replication fork____________
nucleus                                 |
 |__nuclear protein-containing complex__|
replication fork                        |
 |__nuclear replication fork____________|
protein-containing complex              |
 |__nuclear protein-containing complex__|
                                        replication fork protection complex  3 rec.
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Is a nuclear protein-containing complex
Part of nuclear replication fork
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