FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term TRAMP complex ID (Ontology) GO:0031499 (Gene Ontology)
Definition A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.[ PubMed:15173578 PubMed:15828860 PubMed:15935758 PubMed:15935759 PubMed:16373491 PubMed:16374505 PubMed:16431988 PubMed:16973437 PubMed:17410208 PubMed:17652137 ]
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       4
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 Genes
 TRAMP complex (all annotations which use CV term, excluding "NOT" statements)       4
     part_of | TRAMP complex       4
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nucleus_____________________
protein-containing complex__|
                            nuclear protein-containing complex
                             |__TRAMP complex  4 rec.
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Is a nuclear protein-containing complex
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Synonyms
  • "TRAMP4 complex" NARROW
    "TRAMP5 complex" NARROW
    "Trf4 complex" NARROW
    "Trf4 poly(A) polymerase complex" NARROW
    "Trf4p-Air2p-Mtr4p polyadenylation complex" NARROW
Secondary IDs
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Wikipedia:TRAMP_complex