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| Term | heterochromatin formation | ID (Ontology) | GO:0031507 (Gene Ontology) |
| Definition | An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.[ PubMed:25192661 PubMed:33827924 ] | ||
| Also Known As | "chromatin silencing" ; "chromatin-mediated silencing" ; "establishment of heterochromatin architecture" (for all, see Synonyms field below) | ||
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| Is a |
cellular component assembly negative regulation of gene expression, epigenetic heterochromatin organization |
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| Reactome:R-HSA-5334118 "DNA methylation" | |||