FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term pericentric heterochromatin formation ID (Ontology) GO:0031508 (Gene Ontology)
Definition The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA.[ PubMed:14612388 PubMed:20206496 PubMed:22729156 ]
Also Known As "centromere chromatin silencing" ; "centromeric heterochromatin biosynthesis" ; "centromeric heterochromatin formation" (for all, see Synonyms field below)
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       4
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 pericentric heterochromatin formation (all annotations which use CV term, excluding "NOT" statements)       4
     involved_in | pericentric heterochromatin formation       4
 NOT | involved_in | pericentric heterochromatin formation       1
Spanning Tree (Parents/Children)
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  heterochromatin formation
   |__constitutive heterochromatin formation
       |__pericentric heterochromatin formation  7 rec.
           |__regulation of pericentric heterochromatin formation 2 rec.
           |   |__positive regulation of pericentric heterochromatin formation 1 rec.
           |__siRNA-mediated pericentric heterochromatin formation 2 rec.
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Is a constitutive heterochromatin formation
Part of
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Synonyms
  • "centric heterochromatin formation" RELATED
    "centromere chromatin silencing" EXACT
    "centromeric heterochromatin biosynthesis" EXACT
    "centromeric heterochromatin formation" EXACT
    "centromeric silencing" EXACT
    "chromatin silencing at centromere" EXACT
    "chromatin silencing at centromere outer repeat region" NARROW
    "chromatin silencing at pericentric region" RELATED
    "heterochromatic silencing at centromere" EXACT
    "pericentric heterochromatin assembly" EXACT
Secondary IDs
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