FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

pericentric heterochromatin formation

ID (Ontology)

GO:0031508 (Gene Ontology)

Definition

The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA.[ PubMed:14612388 PubMed:20206496 PubMed:22729156 ]

Also Known As

"centromere chromatin silencing" ; "centromeric heterochromatin biosynthesis" ; "centromeric heterochromatin formation" (for all, see Synonyms field below)

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
pericentric heterochromatin formation (all annotations which use CV term, excluding "NOT" statements)
involved_in \| pericentric heterochromatin formation
NOT \| involved_in \| pericentric heterochromatin formation

Spanning Tree (Parents/Children)

  heterochromatin formation
   |__constitutive heterochromatin formation
       |__pericentric heterochromatin formation  7 rec.
           |__regulation of pericentric heterochromatin formation 2 rec.
           |   |__positive regulation of pericentric heterochromatin formation 1 rec.
           |__siRNA-mediated pericentric heterochromatin formation 2 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	constitutive heterochromatin formation
Part of
Synonyms & Secondary IDs
Synonyms
	"centric heterochromatin formation" RELATED "centromere chromatin silencing" EXACT "centromeric heterochromatin biosynthesis" EXACT "centromeric heterochromatin formation" EXACT "centromeric silencing" EXACT "chromatin silencing at centromere" EXACT "chromatin silencing at centromere outer repeat region" NARROW "chromatin silencing at pericentric region" RELATED "heterochromatic silencing at centromere" EXACT "pericentric heterochromatin assembly" EXACT
Secondary IDs

External Crossreferences & Linkouts