FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term MutLalpha complex ID (Ontology) GO:0032389 (Gene Ontology)
Definition A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
Also Known As"MLH1/PMS2 complex" ; "MutL-alpha complex"
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 MutLalpha complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | MutLalpha complex       --
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intracellular anatomical structure
 |__mismatch repair complex_____________
nucleus                                 |
 |__nuclear protein-containing complex__|
protein-containing complex              |
 |__mismatch repair complex_____________|
 |__nuclear protein-containing complex__|
                                        MutLalpha complex  3 rec.
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Is a mismatch repair complex
nuclear protein-containing complex
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Synonyms
  • "MLH1/PMS2 complex" EXACT
    "MMR complex" BROAD
    "MutL-alpha complex" EXACT
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