FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term purine-rich negative regulatory element binding ID (Ontology) GO:0032422 (Gene Ontology)
Definition Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.[ PubMed:9819411 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 purine-rich negative regulatory element binding (all annotations which use CV term, excluding "NOT" statements)       1
     enables | purine-rich negative regulatory element binding       1
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transcription regulatory region nucleic acid binding__
sequence-specific double-stranded DNA binding_________|
                                                      transcription cis-regulatory region binding
                                                       |__purine-rich negative regulatory element binding  1 rec.
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Is a transcription cis-regulatory region binding
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Synonyms
  • "PNR element binding" BROAD
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