FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term negative regulation of type I interferon production ID (Ontology) GO:0032480 (Gene Ontology)
Definition Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Also Known As"down regulation of type I interferon production" ; "down-regulation of type I interferon production" ; "downregulation of type I interferon production" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 negative regulation of type I interferon production (all annotations which use CV term, excluding "NOT" statements)
     involved_in | negative regulation of type I interferon production
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regulation of cytokine production
 |__negative regulation of cytokine production___________
 |__regulation of type I interferon production___________|
negative regulation of gene expression                   |
 |__negative regulation of cytokine production___________|
type I interferon production                             |
 |__regulation of type I interferon production___________|
negative regulation of multicellular organismal process  |
 |__negative regulation of cytokine production___________|
                                                         negative regulation of type I interferon production  1 rec.
                                                          |__negative regulation of interferon-alpha production
                                                          |__negative regulation of interferon-beta production
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Is a negative regulation of cytokine production
regulation of type I interferon production
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Synonyms
  • "down regulation of type I interferon production" EXACT
    "down-regulation of type I interferon production" EXACT
    "downregulation of type I interferon production" EXACT
    "inhibition of type I interferon production" NARROW
    "negative regulation of type I IFN production" EXACT
Secondary IDs
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Reactome:R-HSA-936440 "Negative regulators of DDX58/IFIH1 signaling"