FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term membrane insertase activity ID (Ontology) GO:0032977 (Gene Ontology)
Definition Binds transmembrane domain-containing proteins and mediates their integration into a membrane.[ PubMed:14739936 PubMed:29809151 PubMed:30415835 PubMed:32459176 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 membrane insertase activity (all annotations which use CV term, excluding "NOT" statements)
     contributes_to | membrane insertase activity       --
     enables | membrane insertase activity       --
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  molecular carrier activity
   |__protein carrier activity
       |__membrane insertase activity  27 rec.
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Reactome:R-HSA-1268025 "SAM50 complex inserts proteins into mitochondrial outer membrane"
Reactome:R-HSA-1299482 "TIMM23 SORT inserts proteins into inner membrane"
Reactome:R-HSA-1307803 "TIMM22 inserts proteins into inner membrane"
Reactome:R-HSA-9902096 "COX18 inserts nascent MT-CO2 in COX20:TMEM77"
Reactome:R-HSA-9906955 "MT-ND4 is translated"
Reactome:R-HSA-9926981 "Bam complex inserts Hbp into outer membrane"