FB2026_03 , released September 17, 2026
CV Term Report
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Term proton-transporting V-type ATPase, V1 domain ID (Ontology) GO:0033180 (Gene Ontology)
Definition A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.[ ISBN:0716743663 PubMed:16449553 ]
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 proton-transporting V-type ATPase, V1 domain (all annotations which use CV term, excluding "NOT" statements)
     part_of | proton-transporting V-type ATPase, V1 domain
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proton-transporting two-sector ATPase complex
 |__proton-transporting V-type ATPase complex________________________
 |__proton-transporting two-sector ATPase complex, catalytic domain__|
cation-transporting ATPase complex                                   |
 |__proton-transporting V-type ATPase complex________________________|
membrane protein complex                                             |
 |__proton-transporting two-sector ATPase complex, catalytic domain__|
ATPase complex                                                       |
 |__proton-transporting V-type ATPase complex________________________|
                                                                     proton-transporting V-type ATPase, V1 domain  14 rec.
                                                                      |__plasma membrane proton-transporting V-type ATPase, V1 domain
                                                                      |__vacuolar proton-transporting V-type ATPase, V1 domain 13 rec.
                                                                          |__lysosomal proton-transporting V-type ATPase, V1 domain
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Is a proton-transporting two-sector ATPase complex, catalytic domain
Part of proton-transporting V-type ATPase complex
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