FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term protein lysine deacetylase activity ID (Ontology) GO:0033558 (Gene Ontology)
Definition Catalysis of the reaction: Removal of an acetyl group from a lysine residue in a protein.[ PubMed:27296530 ]
Also Known As "protein deacetylase activity"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       4
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 protein lysine deacetylase activity (all annotations which use CV term, excluding "NOT" statements)       4
     enables | protein lysine deacetylase activity       4
Spanning Tree (Parents/Children)
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catalytic activity
 |__catalytic activity, acting on a protein__
deacylase activity                           |
 |__deacetylase activity_____________________|
                                             protein lysine deacetylase activity  13 rec.
                                              |__histone deacetylase activity 13 rec.
                                              |   |__histone deacetylase activity, hydrolytic mechanism(+) 6 rec.
                                              |   |__histone deacetylase activity, NAD-dependent(+) 6 rec.
                                              |   |__histone H3K deacetylase activity(+) 3 rec.
                                              |   |__histone H4K deacetylase activity(+) 4 rec.
                                              |__tubulin deacetylase activity
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Is a deacetylase activity
catalytic activity, acting on a protein
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Synonyms
  • "protein deacetylase activity" EXACT
Secondary IDs
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Reactome:R-HSA-5693092 "Unknown deacetylase deacetylates 7K-BACE1(46-501)"
Reactome:R-HSA-8952069 "HDAC4 deacetylates RUNX3"
Reactome:R-HSA-9626962 "SIRT1 deacetylates FOXO1"
Reactome:R-HSA-9701565 "HDACs deacetylate p-STAT3 dimers"
Reactome:R-HSA-9825772 "SIRT1 deacetylates HINT1 dimer"
Reactome:R-HSA-9841847 "SIRT3 deacetylates Ac-K272,K290-FOXO3"
RHEA:58108