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| Term | TSC1-TSC2 complex | ID (Ontology) | GO:0033596 (Gene Ontology) | |||||||||||
| Definition | A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.[ PubMed:10585443 PubMed:17121544 PubMed:9580671 ] | |||||||||||||
| Also Known As | "tuberin-hamartin complex" ; "tuberous sclerosis complex" | |||||||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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cellular_component |__protein-containing complex__ cytoplasm | |__cytosol_____________________| cellular anatomical structure | |__cytosol_____________________| TSC1-TSC2 complex 4 rec. |
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| Is a | protein-containing complex | ||
| Part of | cytosol | ||
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