FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

DNA 5'-adenosine monophosphate hydrolase activity

ID (Ontology)

GO:0033699 (Gene Ontology)

Definition

Catalysis of the reactions: a 5'-end adenosine-5'-diphospho-5'-2'-deoxyribonucleoside-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + AMP + 2 H+; and: a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O = a 5'-end 5'-phospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H+. Nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.[ EC:3 PubMed:16547001 PubMed:17276982 ]

Also Known As

"DNA 5'-adenylate hydrolase activity"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
DNA 5'-adenosine monophosphate hydrolase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| DNA 5'-adenosine monophosphate hydrolase activity

Spanning Tree (Parents/Children)

  hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
   |__pyrophosphatase activity
       |__DNA 5'-adenosine monophosphate hydrolase activity  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	pyrophosphatase activity
Part of
Synonyms & Secondary IDs
Synonyms
	"AMP-removal activity" RELATED "DNA 5'-adenylate hydrolase activity" EXACT "DNA adenylate hydrolysis activity" BROAD "DNA de-adenylation" RELATED "DNA deadenylation" RELATED
Secondary IDs

External Crossreferences & Linkouts
	EC:3.6.1.71 RHEA:52128 RHEA:52132