FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term peptide-methionine (R)-S-oxide reductase activity ID (Ontology) GO:0033743 (Gene Ontology)
Definition Catalysis of the reaction: L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol.
Also Known As "protein-methionine-R-oxide reductase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 peptide-methionine (R)-S-oxide reductase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | peptide-methionine (R)-S-oxide reductase activity
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catalytic activity
 |__catalytic activity, acting on a protein_____________________________________________
oxidoreductase activity, acting on a sulfur group of donors                             |
 |__oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor__|
                                                                                        peptide-methionine (R)-S-oxide reductase activity  1 rec.
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Is a oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
catalytic activity, acting on a protein
Part of
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Synonyms
  • "methionine S-oxide reductase (R-form oxidizing) activity" RELATED[ EC:1 ]
    "methionine S-oxide reductase activity" BROAD[ EC:1 ]
    "methionine sulfoxide reductase activity" BROAD[ EC:1 ]
    "methionine sulfoxide reductase B activity" NARROW[ EC:1 ]
    "MsrB" RELATED[ EC:1 ]
    "peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity" RELATED[ EC:1 ]
    "PilB" RELATED[ EC:1 ]
    "pMRsr" RELATED[ EC:1 ]
    "pMSR" RELATED[ EC:1 ]
    "protein-methionine-R-oxide reductase activity" EXACT
    "selenoprotein R" RELATED[ EC:1 ]
    "SelR" RELATED[ EC:1 ]
    "SelX" RELATED[ EC:1 ]
Secondary IDs
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EC:1.8.4.12
KEGG_REACTION:R07607
MetaCyc:1.8.4.12-RXN
Reactome:R-HSA-5676917 "MRSBs reduce L-methyl-(R)-S-oxide to L-methionine"
RHEA:24164