FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ID (Ontology) GO:0033764 (Gene Ontology)
Definition Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (all annotations which use CV term, excluding "NOT" statements)       1      1
     enables | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor       --       1
Spanning Tree (Parents/Children)
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oxidoreductase activity
 |__steroid dehydrogenase activity_________________________________________________________
oxidoreductase activity, acting on CH-OH group of donors                                   |
 |__oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor__|
                                                                                         steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor  12 rec.
                                                                                          |__3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] activity
                                                                                          |__3-beta-hydroxy-5-alpha-steroid dehydrogenase (NADP+) activity
                                                                                          |__3-beta-hydroxy-5-beta-steroid dehydrogenase (NADP+) activity
                                                                                          |__3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity 1 rec.
                                                                                          |   |__cholesterol dehydrogenase (NAD+) activity
                                                                                          |__3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity 8 rec.
                                                                                          |__3-beta-hydroxysteroid dehydrogenase [NAD(P)+]/C4-decarboxylase activity
                                                                                          |   |__3-beta-hydroxysteroid dehydrogenase (NAD+)/C4-decarboxylase activity
                                                                                          |__5-alpha-androstane-3-beta,17-beta-diol dehydrogenase (NADP+) activity
                                                                                          |__7-beta-hydroxysteroid dehydrogenase (NADP+) activity
                                                                                          |__11-beta-hydroxysteroid dehydrogenase (NAD+) activity
                                                                                          |__11-beta-hydroxysteroid dehydrogenase (NADP+) activity
                                                                                          |   |__cortisol dehydrogenase (NADP+) activity
                                                                                          |__12-beta-hydroxysteroid dehydrogenase (NADP+) activity
                                                                                          |__17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity
                                                                                          |__17-beta-hydroxysteroid dehydrogenase (NAD+) activity 1 rec.
                                                                                          |   |__testosterone dehydrogenase (NAD+) activity 1 rec.
                                                                                          |__17-beta-hydroxysteroid dehydrogenase (NADP+) activity 8 rec.
                                                                                          |   |__testosterone dehydrogenase (NADP+) activity
                                                                                          |__androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity
                                                                                          |__androsterone dehydrogenase [NAD(P)+] activity
                                                                                          |__chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity
                                                                                          |__cholate 7-alpha-dehydrogenase (NAD+) activity
                                                                                          |__cholate 12-alpha dehydrogenase (NADP+) activity
                                                                                          |__estradiol 17-alpha-dehydrogenase [NAD(P)+] activity
                                                                                          |__estradiol 17-beta-dehydrogenase [NAD(P)+] activity 9 rec.
                                                                                          |__isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity 1 rec.
                                                                                          |__pregnan-21-ol dehydrogenase (NAD+) activity
                                                                                          |__pregnan-21-ol dehydrogenase (NADP+) activity
                                                                                          |__ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity 1 rec.
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Is a steroid dehydrogenase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
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Reactome:R-HSA-9758682 "AKR1C1 hydrogenates PREDN,PREDL"