FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity ID (Ontology) GO:0033925 (Gene Ontology)
Definition Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity       1
Spanning Tree (Parents/Children)
Only view relationship: 
  hydrolase activity, acting on glycosyl bonds
   |__hydrolase activity, hydrolyzing O-glycosyl compounds
       |__mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity  1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a hydrolase activity, hydrolyzing O-glycosyl compounds
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity" RELATED[ EC:3 ]
    "endo-beta-(1->4)-N-acetylglucosaminidase activity" RELATED[ EC:3 ]
    "endo-beta-acetylglucosaminidase activity" RELATED[ EC:3 ]
    "endo-beta-N-acetylglucosaminidase activity" RELATED[ EC:3 ]
    "endo-beta-N-acetylglucosaminidase D activity" RELATED[ EC:3 ]
    "endo-beta-N-acetylglucosaminidase F activity" RELATED[ EC:3 ]
    "endo-beta-N-acetylglucosaminidase H activity" RELATED[ EC:3 ]
    "endo-beta-N-acetylglucosaminidase L activity" RELATED[ EC:3 ]
    "endo-N-acetyl-beta-D-glucosaminidase activity" RELATED[ EC:3 ]
    "endo-N-acetyl-beta-glucosaminidase activity" RELATED[ EC:3 ]
    "endoglycosidase H activity" RELATED[ EC:3 ]
    "endoglycosidase S activity" RELATED[ EC:3 ]
    "glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity" RELATED[ EC:3 ]
    "glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity" RELATED[ EC:3 ]
    "mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity" RELATED[ EC:3 ]
    "mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity" RELATED[ EC:3 ]
    "N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity" RELATED[ EC:3 ]
Secondary IDs
hide External Crossreferences & Linkouts
EC:3.2.1.96
MetaCyc:3.2.1.96-RXN
Reactome:R-HSA-8853379 "ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5)"