FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term phosphatidylcholine phospholipase C activity ID (Ontology) GO:0034480 (Gene Ontology)
Definition Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine.
Also Known As "phosphatidylcholine phospholipase C-type activity" ; "phospholipase C, acting on phosphatidylcholine"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 phosphatidylcholine phospholipase C activity (all annotations which use CV term, excluding "NOT" statements)
     enables | phosphatidylcholine phospholipase C activity
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glycerophospholipase activity__________
phosphoric diester hydrolase activity__|
                                       C-type glycerophospholipase activity
                                        |__phosphatidylcholine phospholipase C activity  1 rec.
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Is a C-type glycerophospholipase activity
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Synonyms
  • "Clostridium oedematiens beta- and gamma-toxins activity" NARROW[ EC:3 ]
    "Clostridium welchii alpha-toxin activity" NARROW[ EC:3 ]
    "heat-labile hemolysin" NARROW[ EC:3 ]
    "lipophosphodiesterase I activity" RELATED[ EC:3 ]
    "phosphatidylcholine cholinephosphohydrolase activity" RELATED
    "phosphatidylcholine phospholipase C-type activity" EXACT
    "phospholipase C, acting on phosphatidylcholine" EXACT
Secondary IDs
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EC:3.1.4.3
MetaCyc:PHOSPHOLIPASE-C-RXN
Reactome:R-HSA-9680388 "CSF1R-associated PLCG2 hydrolyzes phosphatidylcholine"
RHEA:10604
RHEA:45304
RHEA:78939
RHEA:78947