FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity ID (Ontology) GO:0034485 (Gene Ontology)
Definition 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate.[ EC:3 ]
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Genes
 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity (all annotations which use CV term, excluding "NOT" statements)       2
     enables | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity       2
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phosphatidylinositol phosphate phosphatase activity
 |__phosphatidylinositol trisphosphate phosphatase activity__
 |__phosphatidylinositol phosphate 5-phosphatase activity____|
                                                             phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity  2 rec.
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Is a phosphatidylinositol trisphosphate phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
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EC:3.1.3.86
MetaCyc:RXN-10036
Reactome:R-HSA-1675949 "PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane"
RHEA:25528
RHEA:43548
RHEA:43556