FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

cellular response to oxidative stress

ID (Ontology)

GO:0034599 (Gene Ontology)

Definition

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
cellular response to oxidative stress (all annotations which use CV term, excluding "NOT" statements)
involved_in \| cellular response to oxidative stress

Spanning Tree (Parents/Children)

response to stress
 |__response to oxidative stress__________
cellular response to stress               |
 |__cellular response to chemical stress__|
cellular response to chemical stimulus    |
 |__cellular response to chemical stress__|
                                          cellular response to oxidative stress  38 rec.
                                           |__cellular response to hydroperoxide
                                           |   |__cellular response to alkyl hydroperoxide(+)
                                           |   |__cellular response to lipid hydroperoxide
                                           |__cellular response to reactive oxygen species 14 rec.
                                           |   |__cellular response to hydrogen peroxide(+) 2 rec.
                                           |   |__cellular response to oxygen radical(+) 6 rec.
                                           |   |__cellular response to ozone
                                           |   |__cellular response to singlet oxygen(+)
                                           |   |__programmed cell death in response to reactive oxygen species(+)
                                           |__oxidative stress-induced premature senescence
                                           |__positive regulation of translation in response to oxidative stress
                                           |__regulation of cellular response to oxidative stress 5 rec.
                                           |   |__negative regulation of cellular response to oxidative stress(+) 2 rec.
                                           |   |__positive regulation of cellular response to oxidative stress
                                           |   |__regulation of removal of superoxide radicals(+) 1 rec.
                                           |__regulation of translation in response to oxidative stress
                                           |   |__negative regulation of translation in response to oxidative stress
                                           |__symbiont defense to host-produced reactive oxygen species
                                               |__effector-mediated defense to host-produced reactive oxygen species
                                               |__symbiont-mediated detoxification of host-generated reactive oxygen species

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	response to oxidative stress cellular response to chemical stress
Part of
Synonyms & Secondary IDs
Synonyms
	"adaptive response to oxidative stress" NARROW
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-3299685 "Detoxification of Reactive Oxygen Species" Reactome:R-HSA-9707564 "Cytoprotection by HMOX1"