FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term cholesterol O-acyltransferase activity ID (Ontology) GO:0034736 (Gene Ontology)
Definition Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
Also Known As "acylcoenzyme A:cholesterol O-acyltransferase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 cholesterol O-acyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | cholesterol O-acyltransferase activity
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Vocabulary search: maintenance 
  acyltransferase activity, transferring groups other than amino-acyl groups
   |__sterol O-acyltransferase activity
       |__cholesterol O-acyltransferase activity  1 rec.
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Is a sterol O-acyltransferase activity
Part of
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Synonyms
  • "ACAT activity" BROAD[ EC:2 ]
    "acyl coenzyme A-cholesterol-O-acyltransferase activity" RELATED[ EC:2 ]
    "acyl-CoA:cholesterol acyltransferase activity" RELATED[ EC:2 ]
    "acyl-CoA:cholesterol O-acyltransferase activity" RELATED[ EC:2 ]
    "acylcoenzyme A:cholesterol O-acyltransferase activity" EXACT
    "cholesterol acyltransferase activity" BROAD[ EC:2 ]
    "cholesterol ester synthetase activity" RELATED[ EC:2 ]
    "cholesteryl ester synthetase activity" RELATED[ EC:2 ]
Secondary IDs
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KEGG_REACTION:R01461
MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN
Reactome:R-HSA-8876696 "SOAT1,2 transfer acyl group to CHOL forming CHEST"
RHEA:17729
RHEA:41436
RHEA:42792
RHEA:42796
RHEA:42812
RHEA:42816
RHEA:46612
RHEA:46620
RHEA:64320
RHEA:64324
RHEA:64328