FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term regulatory ncRNA-mediated post-transcriptional gene silencing ID (Ontology) GO:0035194 (Gene Ontology)
Definition A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.[ PubMed:11201747 PubMed:11713190 PubMed:15020054 PubMed:15066275 PubMed:18771919 PubMed:32885814 PubMed:33184244 ]
Also Known As "ncRNA-mediated post-transcriptional gene silencing" ; "posttranscriptional gene silencing by RNA" ; "RNA-dependent post-transcriptional gene silencing" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      25
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 regulatory ncRNA-mediated post-transcriptional gene silencing (all annotations which use CV term, excluding "NOT" statements)       1     25
     involved_in | regulatory ncRNA-mediated post-transcriptional gene silencing       --      25
 NOT | involved_in | regulatory ncRNA-mediated post-transcriptional gene silencing       --       6
Spanning Tree (Parents/Children)
Only view relationship: 
post-transcriptional regulation of gene expression
 |__post-transcriptional gene silencing_______
negative regulation of gene expression        |
 |__post-transcriptional gene silencing_______|
 |__regulatory ncRNA-mediated gene silencing__|
                                              regulatory ncRNA-mediated post-transcriptional gene silencing  204 rec.
                                               |__lncRNA-mediated post-transcriptional gene silencing 1 rec.
                                               |__lsiRNA processing
                                               |__miRNA-mediated post-transcriptional gene silencing 167 rec.
                                               |   |__miRNA-mediated gene silencing by inhibition of translation 15 rec.
                                               |   |__miRNA-mediated gene silencing by mRNA destabilization 26 rec.
                                               |   |__pre-miRNA export from nucleus
                                               |   |__regulation of miRNA-mediated gene silencing(+) 12 rec.
                                               |__piRNA-mediated gene silencing by mRNA destabilization 12 rec.
                                               |   |__transposable element silencing by piRNA-mediated mRNA destabilization 8 rec.
                                               |__regulation of post-transcriptional gene silencing by regulatory ncRNA 12 rec.
                                               |   |__negative regulation of post-transcriptional gene silencing by regulatory ncRNA(+) 9 rec.
                                               |   |__positive regulation of post-transcriptional gene silencing by RNA(+) 2 rec.
                                               |   |__regulation of miRNA-mediated gene silencing(+) 12 rec.
                                               |__RNAi-mediated antiviral immune response 5 rec.
                                               |   |__RNAi-mediated antiviral immunity against DNA virus
                                               |   |__RNAi-mediated antiviral immunity against RNA virus 2 rec.
                                               |__siRNA-mediated post-transcriptional gene silencing 1 rec.
                                               |   |__siRNA-mediated gene silencing by inhibition of translation
                                               |   |__siRNA-mediated gene silencing by mRNA destabilization(+) 1 rec.
                                               |__sRNA-mediated post-transcriptional gene silencing
                                               |__transitive RNA interference
                                                   |__3' transitive RNA interference
                                                   |__5' transitive RNA interference
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a post-transcriptional gene silencing
regulatory ncRNA-mediated gene silencing
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "cosuppression" RELATED
    "ncRNA-mediated post-transcriptional gene silencing" EXACT
    "post-transcriptional gene silencing by RNA" RELATED
    "posttranscriptional gene silencing by RNA" EXACT
    "PTGS" BROAD
    "quelling" RELATED
    "RNA interference" BROAD
    "RNA-dependent post-transcriptional gene silencing" EXACT
    "RNA-mediated post-transcriptional gene silencing" EXACT
    "RNA-mediated posttranscriptional gene silencing" EXACT
    "RNAi" BROAD
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-426496 "Post-transcriptional silencing by small RNAs"
Wikipedia:RNA_interference