FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term miRNA processing ID (Ontology) GO:0035196 (Gene Ontology)
Definition A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.[ PubMed:15066275 PubMed:15066283 PubMed:23985560 PubMed:28379604 ]
Also Known As"gene silencing by miRNA, production of miRNAs" ; "microRNA biogenesis" ; "microRNA processing" (for all, see Synonyms field below)
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 miRNA processing (all annotations which use CV term, excluding "NOT" statements)
     involved_in | miRNA processing
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RNA processing____________________________
regulatory ncRNA-mediated gene silencing__|
                                          regulatory ncRNA processing
                                           |__miRNA processing  13 rec.
                                               |__pre-miRNA 3'-end processing 1 rec.
                                               |__pre-miRNA processing 7 rec.
                                               |   |__pre-miRNA 3'-end processing 1 rec.
                                               |   |__regulation of pre-miRNA processing(+) 3 rec.
                                               |__primary miRNA processing 6 rec.
                                               |   |__regulation of primary miRNA processing(+)
                                               |__regulation of miRNA processing 3 rec.
                                                   |__negative regulation of miRNA processing(+) 3 rec.
                                                   |__positive regulation of miRNA processing(+)
                                                   |__regulation of pre-miRNA processing(+) 3 rec.
                                                   |__regulation of primary miRNA processing(+)
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Is a regulatory ncRNA processing
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Synonyms
  • "gene silencing by miRNA, production of miRNAs" EXACT
    "microRNA biogenesis" EXACT
    "microRNA biosynthesis" BROAD
    "microRNA biosynthetic process" BROAD
    "microRNA metabolic process" BROAD
    "microRNA metabolism" BROAD
    "microRNA processing" EXACT
    "microRNA-mediated gene silencing, production of microRNAs" EXACT
    "miRNA biogenesis" RELATED
    "miRNA biosynthetic process" BROAD
    "miRNA maturation" EXACT
    "miRNA-mediated gene silencing, production of miRNAs" EXACT
    "production of microRNAs involved in gene silencing by microRNA" EXACT
    "production of miRNAs involved in gene silencing by miRNA" EXACT
Secondary IDs
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