FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term protein-arginine omega-N asymmetric methyltransferase activity ID (Ontology) GO:0035242 (Gene Ontology)
Definition Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.[ PubMed:14705965 ]
Also Known As"protein arginine omega-N asymmetric methylase activity" ; "protein arginine omega-N asymmetric methyltransferase activity"
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 protein-arginine omega-N asymmetric methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | protein-arginine omega-N asymmetric methyltransferase activity
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protein methyltransferase activity_____
arginine N-methyltransferase activity__|
                                       protein-arginine N-methyltransferase activity
                                        |__protein-arginine omega-N asymmetric methyltransferase activity  6 rec.
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Is a protein-arginine N-methyltransferase activity
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Synonyms
  • "protein arginine omega-N asymmetric methylase activity" EXACT
    "protein arginine omega-N asymmetric methyltransferase activity" EXACT
    "S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega-dimethyl-L-arginine-forming)" RELATED[ EC:2 ]
    "type I PRMT activity" RELATED
    "type I protein arginine methyltransferase activity" RELATED[ EC:2 ]
Secondary IDs
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EC:2.1.1.319
Reactome:R-HSA-9729283 "Nucleoprotein is methylated by PRMT1"
RHEA:48096