FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

synaptic transmission, glutamatergic

ID (Ontology)

GO:0035249 (Gene Ontology)

Definition

The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.

Also Known As

"glutamatergic synaptic transmission"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
synaptic transmission, glutamatergic (all annotations which use CV term, excluding "NOT" statements)
involved_in \| synaptic transmission, glutamatergic

Spanning Tree (Parents/Children)

  anterograde trans-synaptic signaling
   |__chemical synaptic transmission
       |__synaptic transmission, glutamatergic  31 rec.
           |__glutamate secretion, neurotransmission 5 rec.
           |   |__regulation of glutamate secretion, neurotransmission(+) 5 rec.
           |__regulation of synaptic transmission, glutamatergic 9 rec.
               |__negative regulation of synaptic transmission, glutamatergic(+) 1 rec.
               |__positive regulation of synaptic transmission, glutamatergic(+) 4 rec.
               |__regulation of glutamate secretion, neurotransmission(+) 5 rec.

Spanning Tree View Settings
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Relationships
Is a	chemical synaptic transmission
Part of
Synonyms & Secondary IDs
Synonyms
	"glutamatergic synaptic transmission" EXACT
Secondary IDs

External Crossreferences & Linkouts