FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term NuA4 histone acetyltransferase complex ID (Ontology) GO:0035267 (Gene Ontology)
Definition A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).[ PubMed:10966108 PubMed:14966270 ]
Also Known As "TIP60 histone acetylase complex" ; "TIP60 histone acetyltransferase complex"
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT      21
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 Gene Groups Genes
 NuA4 histone acetyltransferase complex (all annotations which use CV term, excluding "NOT" statements)       1     21
     part_of | NuA4 histone acetyltransferase complex       --      21
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  H4 histone acetyltransferase complex
   |__H4/H2A histone acetyltransferase complex
       |__NuA4 histone acetyltransferase complex  22 rec.
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Synonyms
  • "TIP60 histone acetylase complex" EXACT
    "TIP60 histone acetyltransferase complex" EXACT
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