FB2026_03 , released September 17, 2026
CV Term Report
Help Close All Open All
General Information
Term miRNA-mediated gene silencing by inhibition of translation ID (Ontology) GO:0035278 (Gene Ontology)
Definition An RNA interference pathway in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.[ PubMed:14744438 PubMed:15196554 ]
Also Known As"down regulation of translation involved in gene silencing by miRNA" ; "down-regulation of translation involved in gene silencing by miRNA" ; "downregulation of translation involved in gene silencing by miRNA" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

    • Results list data from multiple species. Choose a record type above to open its HitList.
Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 miRNA-mediated gene silencing by inhibition of translation (all annotations which use CV term, excluding "NOT" statements)
     involved_in | miRNA-mediated gene silencing by inhibition of translation
Spanning Tree (Parents/Children)
Only view relationship:
Vocabulary search 
regulation of translation
 |__negative regulation of translation_________________________
negative regulation of gene expression                         |
 |__negative regulation of translation_________________________|
regulatory ncRNA-mediated post-transcriptional gene silencing  |
 |__miRNA-mediated post-transcriptional gene silencing_________|
negative regulation of protein metabolic process               |
 |__negative regulation of translation_________________________|
                                                               miRNA-mediated gene silencing by inhibition of translation  18 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a negative regulation of translation
miRNA-mediated post-transcriptional gene silencing
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "down regulation of translation involved in gene silencing by miRNA" EXACT
    "down-regulation of translation involved in gene silencing by miRNA" EXACT
    "downregulation of translation involved in gene silencing by miRNA" EXACT
    "gene silencing by miRNA, negative regulation of translation" EXACT
    "inhibition of translation involved in gene silencing by miRNA" NARROW
    "miRNA mediated inhibition of translation" EXACT
    "miRNA-mediated gene silencing, negative regulation of translation" RELATED
    "negative regulation of translation involved in gene silencing by microRNA" EXACT
Secondary IDs
hide External Crossreferences & Linkouts