FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

oxidative RNA demethylase activity

ID (Ontology)

GO:0035515 (Gene Ontology)

Definition

Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.[ PubMed:12594517 PubMed:16482161 PubMed:18775698 ]

Also Known As

"2-oxoglutarate-dependent RNA demethylase"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
oxidative RNA demethylase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| oxidative RNA demethylase activity

Spanning Tree (Parents/Children)

catalytic activity
 |__demethylase activity_______________________________________________________________________________
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen  |
 |__2-oxoglutarate-dependent dioxygenase activity______________________________________________________|
dioxygenase activity                                                                                   |
 |__2-oxoglutarate-dependent dioxygenase activity______________________________________________________|
catalytic activity, acting on a nucleic acid                                                           |
 |__catalytic activity, acting on RNA__________________________________________________________________|
                                                                                         oxidative RNA demethylase activity  1 rec.
                                                                                          |__mRNA N1-methyladenosine dioxygenase activity
                                                                                          |__mRNA N6-methyladenosine dioxygenase activity
                                                                                          |__tRNA demethylase activity

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	2-oxoglutarate-dependent dioxygenase activity demethylase activity catalytic activity, acting on RNA
Part of
Synonyms & Secondary IDs
Synonyms
	"2-oxoglutarate-dependent RNA demethylase" EXACT[ PubMed:17991826 ]
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-8857692 "RNA demethylases demethylate N6-methyladenosine RNA"