FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity ID (Ontology) GO:0035597 (Gene Ontology)
Definition Catalysis of the reaction: N(6)-dimethylallyladenosine(37) in tRNA + [sulfur carrier]-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + [sulfur carrier]-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H+.[ PubMed:20472640 ]
Also Known As"i6A methylthiotransferase activity" ; "N6-isopentenyladenosine methylthiotransferase activity" ; "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity
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alkylthioltransferase activity
 |__methylthiotransferase activity________
catalytic activity, acting on RNA         |
 |__catalytic activity, acting on a tRNA__|
                                          tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity  1 rec.
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Is a methylthiotransferase activity
catalytic activity, acting on a tRNA
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Synonyms
  • "i6A methylthiotransferase activity" EXACT[ PubMed:20472640 ]
    "N6-isopentenyladenosine methylthiotransferase activity" EXACT
    "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase activity" EXACT
Secondary IDs
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EC:2.8.4.3
RHEA:37067