FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

mitochondrial prohibitin complex

ID (Ontology)

GO:0035632 (Gene Ontology)

Definition

A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.[ PubMed:12237468 PubMed:21164222 ]

Also Known As

"mitochondrial inner membrane prohibitin complex"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
mitochondrial prohibitin complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| mitochondrial prohibitin complex

Spanning Tree (Parents/Children)

mitochondrial inner membrane______________
membrane protein complex__________________|
mitochondrial protein-containing complex__|
                                          inner mitochondrial membrane protein complex
                                           |__mitochondrial prohibitin complex  2 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	inner mitochondrial membrane protein complex
Part of
Synonyms & Secondary IDs
Synonyms
	"mitochondrial inner membrane prohibitin complex" EXACT
Secondary IDs

External Crossreferences & Linkouts