FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term cardiolipin phospholipase D activity ID (Ontology) GO:0035755 (Gene Ontology)
Definition Catalysis of the reaction: a cardiolipin + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate + H(+).[ PubMed:17028579 PubMed:21397848 ]
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 cardiolipin phospholipase D activity (all annotations which use CV term, excluding "NOT" statements)
     enables | cardiolipin phospholipase D activity
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glycerophospholipase activity__________
phosphoric diester hydrolase activity__|
                                       D-type glycerophospholipase activity
                                        |__cardiolipin phospholipase D activity  1 rec.
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Is a D-type glycerophospholipase activity
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Synonyms
  • "cardiolipin hydrolase activity" BROAD
Secondary IDs
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Reactome:R-HSA-8954398 "PLD6 dimer hydrolyses cardiolipin to PA and PG"
RHEA:44884